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Thyrotoxic Crisis or Thyroid Storm : Management

Thyrotoxic Crisis or Thyroid Storm : Management

AKA Hyperthyroid Crisis or Thyroid storm
Presents as a life threatening exacerbation of Hyperthyroidism.Despite early recognition and treatement, mortality is still 10 % and upto 30% when presents with Hyperthermia, Cardiac failure and arrhythmia.
Precipitating Factors of Thyrotoxic Crisis-

Acute illness (e.g. stroke, infection, trauma, Diabetic Ketoacidosis or DKA)
Surgery (especially subtotal thyroidectomy when patient is ill-prepared)
Radioiodine treatment of a patient with partially treated …

Giardiasis: A cause of Chronic diarrhea and malabsorption

Giardiasis: A cause of Chronic diarrhea and malabsorption

Introduction-
Giardiasis is the Infection of the upper small intestine caused by a Flagellate Protozoan , Giardia lamblia ( aka G. intestinalis or G. duodenalis).
Epidemiology-

Occurs Worldwide, most abundantly in areas with poor sanitation.
Persons of all ages area affected, but is particularly high among children.

Life Cycle and Pathogenesis-
Organism occurs in faeces. Only the cyst is infectious, trophozoites are destroyed by gastric acidity. …

Unfractioned Heparin and Low Molecular Weight Heparins

Unfractioned Heparin and Low Molecular Weight Heparins

Unfractioned Heparin-
Unfractioned Heparin- is derived from  porcine intestinal mucosa or bovine lung tissue. UFH catalyzises that inactivation of thrombin and factor Xa by inhibiting Anti-thrombin III.  At usual dose it prolongs TT and aPTT and has a minimal effect on PT/INR.
Benefits of UFH-

1. The effect of UFH normalizes within hours of discontinuation
2. It is reversible with Protamine Sulphate.
3. Can be …

Kluver-Bucy Syndrome

Kluver-Bucy Syndrome

Kluver-Bucy Syndrome is a rare neurobehavioral disorder associated with bilateral destruction of the anterior part of the temporal lobes of the brain. This removes not only, portions of temporal cortex but also of the amygdalas that lie inside these parts of the temporal lobe.
Anatomic Basis:
Amygdala lies deep within medial temporal lobes of the brain. The centromedial amygdala projects through the …

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