Antimicrobial resistance on the rise: Are we running out of drugs?
The world of modern medicine was transformed in 1928 by Sir Alexander Fleming’s accidental discovery of penicillin, introducing the age of antibiotics. Today again the world of medicine teeters on the edge of another change, the post-antibiotic era. Sir Fleming predicted this ominous scenario in his Noble prize acceptance speech in 1945, warning that negligent […]
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Side Effects Of Anabolic Steroids
Anabolic steroids or anabolic-androgenic steroids (AAS), are synthetic forms of the male sex hormone testosterone. They mimic the effects of the male steroids testosterone and dihydrotestosterone. They increase protein synthesis within cells, which results in the buildup of cellular tissue (especially in muscles). Taking doses 10 to 100 times the amount prescribed by doctors for […]
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Opioid Poisoning and its Emergency Management
Opioids are among the commonly misused substance by drug abusers around the world. Opioid comes in various forms – Heroin , Morphine, Methadone, Coedine, Pethidine, Dihydrocoedeine. These are a class of drugs derived from the extracts of plant- opium poppy. Used as Analgesics but most opiates give a feeling of euphoria and a degree of […]
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Newer Antibiotics and their Uses – Review
FDA Approved Antibiotics which are marketed internationally. The problem of the antibiotic resistance has been over-viewed in the previous article. Here are the latest antibiotics in current use. Oxazolidinones In clinical use: Linezolid In clinical trials: Radezolid, torezolid. Effective against Organisms- –gram-positive bacteria including MRSA, VRE and Streptococcus pneumoniae. –Mycobacterium tuberculosis and Nocardia. Linezolid- 1st to be […]
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Antibiotic Resistance and Newer antibiotics- An overview
The need for novel antibacterials is a desparation today because of increasing resistance to the older ones.Three classes of drug-resistant bacteria are a major cause of concern- –Methicillin -resistantStaphylococcus aureus (MRSA), –multidrug-resistant (MDR) and pan-drug-resistant (PDR) gram-negative bacteria, which include strains of Acinetobacter baumannii, Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa, –MDR and extensively-drug-resistant (XDR) strains of Mycobacterium tuberculosis (MDR-TB […]
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How to Study Pharmacology : Study plan MBBS
A complete new and difficult topic and relatively unheard of terminologies and words are met in the subject called Pharmacology. This is what makes it one of the most difficult subject to learn and often needs mugging up of names of drugs. But as you become familiar to the terminologies and start getting comfortable with […]
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Thalidomide induced Teratogenecity: Phocomelia
Thalidomide taken during Pregnancy, in 1960s caused a horror outbreak of a birth defects of limbs called Phocomelia Labeled as pregnancy category X, the teratogenicity of thalidomide is most severe. Lipid soluble and readily crosses the placenta, so it should never be taken by pregnant women or those who could become pregnant. Thalidomide was released […]
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Laxative abuse and habituation
Laxatives (purgatives, aperients) are foods, compounds, or medication that promote and facilitate bowel evacuation by acting locally to stimulate intestinal peristalsis, to soften bowel contents, or both. Laxatives are generally indicated in constipation (bowel movements that are infrequent and/or hard to pass). With constipation stools are usually hard, dry, small in size, and difficult to […]
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Antibiotic Resistance : The War Has Begun
War Fiction By Medchrome In 2012, war broke out. Soon the war was fought all over the world. This time the enemy were not human neither aliens. They were invisible , tiny but lethal. The war was between doctors and bacteria. Doctors used every weapon they had – antibiotics but the bacteria had become too […]
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