Major Archive

Sickle Cell Disease: A Primer

Background: Sickle cell disease (SCD) or sickle cell anemia (SCA) is a hemoglobinopathy wherein abnormal hemoglobin is produced. It was first noted by James Herrick a medical student of African descent in 1911, when he discovered sickle-shaped erythrocytes while examining a student’s blood. Linus ...Read More

Chicken pox and its complications

Varicella-zoster virus (VZV) Causes-  primary, latent, and recurrent infections. Primary infection – Varicella (chickenpox) A lifelong latent infection of sensory ganglion neurons. Reactivation of the latent infection – Herpes zoster (shingles). Epidemiology Most children are infected by 15 yr of age, with fewer than 5% ...Read More

Delayed wound healing in Diabetes Mellitus

Diabetes Mellitus (DM) is a chronic disorder of glucose metabolism with hyperglycemia triggered by conditions associated with a relative or absolute insulin deficiency. Insulin is an anabolic hormone with profound effects on the metabolism of carbohydrate, fat and protein. Less severe hyperglycemia is called ...Read More