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Antimicrobial resistance on the rise: Are we running out of drugs?

April 14, 2016

The world of modern medicine was transformed in 1928 by Sir Alexander Fleming’s accidental discovery of penicillin, introducing the age of antibiotics. Today again the world of medicine teeters on the edge of another change, the post-antibiotic era. Sir Fleming predicted this ominous scenario in his Noble prize acceptance speech in 1945, warning that negligent […]

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Diagnosis of Extrapulmonary Tuberculosis: Need of the hour

March 23, 2016

The burden of tuberculosis (TB) in India is the largest in the world with around 23% of the global 9.6 million affected people in 2014.While pulmonary tuberculosis (PTB) is the most common presentation, extrapulmonary tuberculosis (EPTB) accounts for a significant proportion of tuberculosis cases worldwide. In India, 10-15% of cases in immunocompetent individuals are EPTB, […]

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Brachial Plexus And Its Injury

January 17, 2016

Definition: A network of spinal nerves that originates in the back of the neck, extends through the axilla (armpit), and gives rise to nerves to the upper limb. The brachial plexus is formed by the union of portions of the 5th through 8th cervical nerves (C5-C8) and the first thoracic nerve (T1), all of which […]

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Kluver-Bucy Syndrome

December 27, 2015

Kluver-Bucy Syndrome is a rare neurobehavioral disorder associated with bilateral destruction of the anterior part of the temporal lobes of the brain. This removes not only, portions of temporal cortex but also of the amygdalas that lie inside these parts of the temporal lobe. Anatomic Basis: Amygdala lies deep within medial temporal lobes of the […]

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Side Effects Of Anabolic Steroids

October 3, 2014

Anabolic steroids or anabolic-androgenic steroids (AAS), are synthetic forms of the male sex hormone testosterone. They mimic the effects of the male steroids testosterone and dihydrotestosterone. They increase protein synthesis within cells, which results in the buildup of cellular tissue (especially in muscles). Taking doses 10 to 100 times the amount prescribed by doctors for […]

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opioid misuse

Opioid Poisoning and its Emergency Management

January 4, 2014

Opioids are among the commonly misused substance by drug abusers around the world. Opioid comes in various forms – Heroin , Morphine, Methadone, Coedine, Pethidine, Dihydrocoedeine. These are a class of drugs derived from the extracts of plant- opium poppy. Used as Analgesics but most opiates give a feeling of euphoria and a degree of […]

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Rheumatoid Factor (RA Factor) and Its Diagnostic Importance

October 13, 2013

A presentaion on rheumatoid factor and its significance in diagnosis of rheumatoid arthritis by students of Kist Medical College Objectives To define Rheumatoid Factor . To explain briefly its significance in the diagnosis of rheumatoid arthritis. Rheumatoid factor Rheumatoid factor (RF) is an autoantibody that is directed against organism’s own tissues, most relevant in rheumatoid […]

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Newer Antibiotics and their Uses – Review

September 25, 2013

FDA Approved Antibiotics which are marketed internationally. The problem of the antibiotic resistance has been over-viewed in the previous article. Here are the latest antibiotics in current use. Oxazolidinones In clinical use: Linezolid   In clinical trials: Radezolid, torezolid. Effective against Organisms- –gram-positive bacteria including MRSA, VRE and Streptococcus pneumoniae. –Mycobacterium tuberculosis and Nocardia. Linezolid- 1st to be […]

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Antibiotic Resistance and Newer antibiotics- An overview

September 17, 2013

The need for novel antibacterials is a desparation today because of increasing resistance to the older ones.Three classes of drug-resistant bacteria are a major cause of concern- –Methicillin -resistantStaphylococcus aureus (MRSA), –multidrug-resistant (MDR) and pan-drug-resistant (PDR) gram-negative bacteria, which include strains of Acinetobacter baumannii, Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa, –MDR and  extensively-drug-resistant (XDR) strains of Mycobacterium tuberculosis (MDR-TB […]

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