Pemphigoids
PEMPHIGOIDS:
disorder characterized by the eruption of multiple , tense bullae either over an erythematous or normal skin in an elderly patient.
- Age Old: ( 6-8 decades)
- General Health: Good
- Site : Flexural ( thigh, flexural of arms, axilla, groins)
- Mouth Ulcers: Rare
- Nature of Blisters: Large and tense over normal, urticarial or erythematous base. Localised or widespread. Rupture and show tendency to heal.
- Self limiting lesions
- Antibodies: IgGAb at BM zone
Variants:
- Vesicular pemphigoid
- Localised bullous pemphigoid
- Vegetans- massive purulent, verrucous, vegetative plaques.
- Nodular: linear bullous dermatosis, EpidermolysisBullosaAcquisite.
Diagnosis:
- Clinical
- Histopathology
- Immunofloresence.
Treatment:
Topical :
- Corticosteroid
- Antibiotic
Systemic :
- Prednisolone 40-60 mg
- Antihistaminics
Prognosis: good