Dermatology Archive

Hereditary and Acquired Icthyosis Vulgaris

Editor Dermatology January 29, 2018

Background: The term ichthyosis is derived from the ancient Greek root ichthys, meaning fish. Hereditary ichthyosis vulgaris is an autosomal dominant genetic disorder first evident in early childhood. It is the most common form of ichthyosis, accounting for more than 95% of ichthyosis cases. ...Read More

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Acne- a disfiguring skin problem

Editor Dermatology April 25, 2014

A common skin problem of adolesence. Acne often disfigures and scar the skin to an extent that may cause depression and low self-confidience among people. • Acne is almost always seen in the teenage years • severity of disease differs per individuals • Peak ...Read More

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Basic Terminologies in Dermatology

Editor Dermatology February 21, 2011

Description of Primary Skin Lesions Macule: A flat, colored lesion, <2 cm in diameter, not raised above the surface of the surrounding skin. A “freckle,” or ephelid, is a prototype pigmented macule. Patch: A large (>2 cm) flat lesion with a color different from ...Read More

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Vitamin B3- Niacin Deficiency and Pellagra

Editor Dermatology January 2, 2011

Overview of Metabolism- Nicotinamide and nicotinic acid are covered under genre Niacin of which Nicotinamide is essential part of NAD and NADP. NAD and NADP are required in essential biochemical reaction of the body where they act as hydrogen acceptors and donor for many ...Read More

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Penicillin Anaphylaxis : A Dreaded Drug Reaction

Editor Dermatology, Medicine, Pharmacology November 6, 2010

Penicillin or Beta lactam antibiotics are commonly associated with drug reactions which are immunologically mediated reactions. Why does penicillin anaphylaxis occur? The core structure Beta lactams consists of a reactive bicyclic B lactam ring that acts as a hapten by covalently binding to tissue ...Read More

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Psoriasis : Autoimmune disease of Skin

Sulabh Shrestha Dermatology, Pathology June 11, 2010

Psoriasis is a chronic, non-contagious, autoimmune disease involving keratinocyte proliferation along with inflammation and angiogenesis. It is sometimes associated with arthritis, myopathy, enteropathy, spondiolytic joint disease or AIDS. It frequently affects skin of elbows, knees, scalp, lumbosacral areas, intergluteal cleft and glans penis. It ...Read More

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Pemphigoids

Editor Dermatology December 30, 2009

PEMPHIGOIDS: disorder characterized by the eruption of multiple , tense bullae either over an erythematous or normal skin in an elderly patient. Age Old: ( 6-8 decades) General Health: Good Site : Flexural ( thigh, flexural of arms, axilla, groins) Mouth Ulcers: Rare Nature ...Read More

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Pemphigus Vulgaris : A Vesiculobullous Disease

Editor Dermatology December 2, 2009

Overview: Derieved : Greek word pemphix meaning bubble. Named by Wichman in 1791. Pemphigus refers to a group of autoimmune blistering diseases of the skin and mucous membranes characterized by formation of flaccid bullae. . Pathophysiology Mediated by circulating autoantibodies directed against keratinocyte cell ...Read More

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