Pemphigoids

PEMPHIGOIDS:

disorder characterized by the eruption of multiple , tense bullae either over an erythematous or normal skin in an elderly patient.

• Age Old: ( 6-8 decades)
• General Health: Good
• Site : Flexural ( thigh, flexural of arms, axilla, groins)
• Mouth Ulcers: Rare
• Nature of Blisters: Large and tense over normal, urticarial or erythematous base. Localised or widespread. Rupture and show tendency to heal.
• Self limiting lesions
• Antibodies: IgGAb at BM zone

Variants:

1. Vesicular pemphigoid
2. Localised bullous pemphigoid
3. Vegetans- massive purulent, verrucous, vegetative plaques.
4. Nodular: linear bullous dermatosis, EpidermolysisBullosaAcquisite.

Diagnosis:

• Clinical
• Histopathology
• Immunofloresence.

Treatment:

Topical :

• Corticosteroid
• Antibiotic

Systemic :

• Prednisolone 40-60 mg
• Antihistaminics

Prognosis: good