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Category: Biochemistry

Biochemistry

The golden era of genomics and its application in human diseases

Editor March 6, 2018 No Comments

Background: Genomics is an interdisciplinary field of science focusing on the structure, function, evolution, mapping, and editing of genomes. The milestone discovery of the human…

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Biochemistry

Glycogen Metabolism and Glycogen storage Diseases

Sulabh Shrestha June 1, 2013 5 Comments glycogen storage diseaseglycogenesisglycogenolysis

GLYCOGEN: Glycogen is the major storage carbohydrate in animals, corresponding to starch in plants; it is a branched polymer of α-D-glucose. It is stored mainly…

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Biochemistry

Ketone bodies, Ketosis and Ketoacidosis

Editor March 1, 2012 No Comments

Ketone bodies, produced mainly in the mitochondria of liver cells from acetyl-CoA enter blood, provide much of the energy to heart tissue, and during starvation…

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Biochemistry

Polymerase Chain Reaction: Principles and Uses of PCR

Sulabh Shrestha June 21, 2011 5 Comments PCR

The Polymerase Chain Reaction (PCR) is an invitro method of DNA amplification that can rapidly clone (amplify) DNA samples as small as a single molecule.…

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Biochemistry Pharmacology

Therapeutic Use of Enzymes

Sulabh Shrestha December 14, 2010 2 Comments asparaginasepenicillinpenicillin allergystreptokinasetherapeutic use of enzymes

Enzymes are the extremely selective biocatalysts synthesized by living cells. Therapeutic enzymes are those enzymes which can be used medically either isolately or adjunctly with…

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Biochemistry

Isoenzymes and their Diagnostic Importance

Sulabh Shrestha November 27, 2010 2 Comments ALPBiochemistryCPKIsoenzymeIsozymeLDH

Isoenzymes: Also called isozymes Are multiple forms of an enzyme that catalyzes the same reaction Arise through gene duplication Differ in their physical and chemical…

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Biochemistry

CPT I Deficinecy

Editor June 9, 2010 No Comments Carnitine PalmitoyltransferaseCPT I deficinecyCPT1AHypoketotic hpoglycemiaMCT oil

Introduction, cause, symptoms, diagnosis, misdiagnosis and treatments of CPT I deficiency Definition: CPT I (Carnitine palmitoyltransferase I) deficinecy is a rare autosomal recessive metabolic disorder…

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Biochemistry

Hypokalemia : Low potassium levels in Blood

Sulabh Shrestha June 4, 2010 1 Comment bulimiacushing's syndromehypokalemiaparalysisrenal artery stenosis

Causes, effects,  diagnosis, prevention and treatment of hypokalemia Around 95% of the body’s K+ is found inside cells and remaining in the blood. It is…

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