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Acne- a disfiguring skin problem

Acne-  a disfiguring skin problem

A common skin problem of adolesence. Acne often disfigures and scar the skin to an extent that may cause depression and low self-confidience among people.
• Acne is almost always seen in the teenage years
• severity of disease differs per individuals
• Peak severity is in the late teenage years But acne may persist into the third decade and beyond, particularly in females.

Basic Terminologies in Dermatology

Basic Terminologies in Dermatology

Description of Primary Skin Lesions
Macule: A flat, colored lesion, <2 cm in diameter, not raised above the surface of the surrounding skin. A “freckle,” or ephelid, is a prototype pigmented macule. Patch: A large (>2 cm) flat lesion with a color different from the surrounding skin. This differs from a macule only in size.
Papule: A small, solid lesion, …

Vitamin B3- Niacin Deficiency and Pellagra

Vitamin B3- Niacin Deficiency and Pellagra

Overview of Metabolism-
Nicotinamide and nicotinic acid are covered under genre Niacin of which Nicotinamide is essential part of NAD and NADP. NAD and NADP are required in essential biochemical reaction of the body where they act as hydrogen acceptors and donor for many enzymes. Tryptophan is the substrate for this vitamin and it can be synthesized by the body …

Penicillin Anaphylaxis : A Dreaded Drug Reaction

Penicillin Anaphylaxis : A Dreaded Drug Reaction

Penicillin or Beta lactam antibiotics are commonly associated with drug reactions which are immunologically mediated reactions.

Why does penicillin anaphylaxis occur?
The core structure Beta lactams consists of a reactive bicyclic B lactam ring that acts as a hapten by covalently binding to tissue carrier proteins. 95% of tissue bound penicillin is found to be haptenated in the form of benzyl …

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