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Rheumatic Fever and Rheumatic Heart Disease

Definition: Rheumatic fever (RF) is an acute, immunologically mediated, multisystem inflammatory disease involving heart, joints, CNS, skin and other tissues that occurs a few weeks after an episode of group A β-hemolytic streptococcal pharyngitis. Acute rheumatic…

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Myocardial Infarction Made Easy

The 4 Ischemic Heart Diseases caused due to imbalance between supply and demand of the heart for oxygenated blood are: Acute Myocardial Infarction (MI) Angina Pectoris Chronic Ischemic Heart Disease (IHD) Sudden Cardiac Death Myocardial…

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Pathogenesis of Glomerular Injury

Primary Immunopathogenic mechanism: Initiator of the disease process by: Antibody mediated injury: immune complex deposition or cytotoxic antibodies T-cell mediated immune injury: non-immune complex deposition mechanism Secondary immunopathogenic mechanism: Role of mediators of the disease:…

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Morphology of Alcoholic Liver Disease

Alcoholic Liver Disease (ALD) is a term used to describe the spectrum of liver injury associated with acute andchronic alcoholism. The 3 stages of Alcoholic Liver Disease are: Hepatic steatosis (fatty change) Alcoholic hepatitis Alcoholic…