Birth defects are a result of Syndromes, Gene mutations, Infections during pregnancy, toxicities of drugs and metals,and environmental factors. Combinations of these factors often play a role is severe deformities.Here are Six Rarest and most severe congenital anomalies or birth defects seen by mankind.

These pictures were collected from different sources on the internet and some pages in the facebook. Don’t forget to leave the feedback.The Gallery Images ( A- is top left, B is Top right and in the similar order)

A. Profound Fusion of Siamese Twin- A severe deformity of the infant is actually due to a Fused siamese twin. Called Profound fusion of siamese twin. ( Source unclear)

B.”Mermaid syndrome” also known as sirenomelia due to fusion of two limbs. Shiloh Pepin, who was born with fused legs, a rare condition often called “mermaid syndrome, died at the age of10.(The Huffington post)

C. Hydrops Fetalis with Cystic hygroma in neck. A severely deformed child born dead. (this photo was taken yesterday @ al Hilal Hospital in Ramallah … for a 21 week fetus who was aborted”)

D.Harlequin baby-”Harlequin fetus” and “Ichthyosis congenita gravior”, a skin disease, is the most severe form of congenital ichthyosis. Synonymous with Harlequin ichthyosis, ichthyosis congenita, Ichthyosis fetalis,keratosis diffusa fetalis, “Harlequin fetus”,and “Ichthyosis congenita gravior”

E. Synophthalmia- A severly malformed child with cyclopia (cyclocephaly or synophthalmia) is a rare form of holoprosencephaly.

F. Baby named Laxmi, India was born with 4 arms and 4 legs but later corrective surgery was done. Now she is normal.

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Last updated: April 14, 2013

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