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MgSO4 in management of Pre-eclampsia and Eclampsia


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• Take 4 gm MgSO4 IV as 20% solution
• Take one 20ml syringe
• Draw 4 ampules of MgSO4 50%= 8ml= 4gm into the syringe
• Add 12 ml water for inj to make it 20%
• Give IV slowly over 5 minutes
Follow promptly with 10 gm as 50% MgSO4 deep IM
• Take two 10ml syringes
• Draw 5 amp of MgSO4 50% =10ml =5gm into each syringe
• Add 1 ml of 2% Lignocaine in each syringe
• Give deep IM in each buttock
• If further fits occur, give further 2 amp of MgSO4 50% =4ml =2gm IV slowly over 5 minutes
• 5gm as 50% MgSO4 deep IM in alternate buttocks every 4 hrly
• Take one 10ml syringe
• Draw 5 amp of MgSO4 50% =10ml =5gm into the syringe
• Add 1 ml of 2% lignocaine in that syringe
• Give deep IM in alternate buttocks every 4 hrly
• Continue same treatment for 24 hrs after delivery or the last convulsion, whichever is the last

BEFORE REPEATING MgSO4 ALWAYS monitor for toxicity. Withhold or delay if any of the following
• Respiratior rate <16/min
• Patellar reflexes absent
• Urine output < 30ml/hr

If respiratory arrest:
• Assist ventilation with bag and mask or intubation
• Give calcium gluconate 1 gm ( 10ml of 10%) IV slowly until respiration begins.

Source: USAID and ACCESS

Please for Study purpose only, This is not a medical advice or prescription

Tags: eclampsia, Gyne, MgSO4, PET, PIH, pre-eclampsia

Last updated: August 11, 2010

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This entry was posted by on August 11, 2010 at 9:02 pm and filed under Gynae/Obstr category.

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