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Trisomy 21 or Down Syndrome was first described by John Langdon Hayden Down a Physician ( 1828-1896 AD) in The London Hospital in 1866 AD.In 1959, Lejeune and Jacobs et al independently determined -trisomy 21 as cause of Down Syndrome.
March 21st every Year is Marked as ” Down Syndrome Day” – 3rd month 21st
Karyotype-
Trisomy 21: 47 XX or XY …
