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Paracetamol Poisoning In children

May 12, 2010 # 6:08 pm # Emergency Paed, Uncategorized # One Comment
Paracetamol Poisoning In children

Paracetamol  Poisoning In Children:
Paracetamol  is a commonly prescribed drug in Medical practice. It is rapidly absorbed on oral intake and metabolized to sulph and glucoronide  group. Small amount is excreted in Urine.

Mechanism Of Toxiciy:

Paracetamol  is Metabolised to NABQI ( N- Acetyl –p-BenzoQuinimine) . Glutathione detoxifies it into Mercatopuric acid which is excreted in urine.
At Toxic Level, when >70 % …

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