Alcoholic Liver Disease
Alcohol is a toxic substance to the liver and remains one of the most common causes of chronic liver disease.
The spectrum of ALD is broad and a single patient may be affected by more than one of the following conditions;fatty liver, alcoholic hepatitis or alcoholic cirrhosis.
EPIDEMIOLOGY

ALD does not occur below a threshold of 21 units/week in women and …

Also Known as Fulminant Hepatic Failure, it is a Syndrome in which hepatic encephalopathy, characterized by mental changes progressing from confusion to stupor and coma, and results from a sudden severe impairment of hepatic function. According to some authors, Acute liver failure is a broad term and encompasses both fulminant hepatic failure and subfulminant hepatic failure.
Fulminant hepatic failure (FHF) …

Liver Blood supply:—
The liver derives blood from the hepatic artery (20%)  and the portal vein (80%).
The hepatic artery usually arises from the aorta at the coeliac axis and divides into the right and left branches at the hilus.
— —The venous drainage from the liver is by three large hepatic veins  right, middle and left  into the inferior vena cava (IVC), …

Indications for diagnostic paracentesis:

Cirrhotic patients with ascites at admission
Cirrhotic patients with …

Alcohol  are hydroxy derivatives of aliphatic hydrocarbons.
Manufacture:
C6H12 O6 (sugar) —-zymase—-> 2 CO2+ 2C 2 H 5 OH
Metabolism of Alcohol:

Alcohol is metabolized in liver by alcohol dehydrogenase
90% – processed in liver
10% – excreted (eliminated unchanged from kidneys and lungs)
Absorption mostly from small intestine and only 10% from stomach.
Peak effect in 30 to 90 min (30 to 60 min in empty stomach)
Depends  upon:

time …