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Understanding Hypothyroidism

Understanding Hypothyroidism

Thyroid Hormones
The major thyroid hormones are T0-T2 and T3-T4.
T0 through T2 are considered inert hormones. They appear to be byproducts of thyroid hormone synthesis and do not appear to have any function in the body.
T3 and T4 are the hormones associated with hypothyroidism, and they play a crucial role in your metabolism. T3 is the primary hormone used to fuel …

Thyrotoxic Crisis or Thyroid Storm : Management

Thyrotoxic Crisis or Thyroid Storm : Management

AKA Hyperthyroid Crisis or Thyroid storm
Presents as a life threatening exacerbation of Hyperthyroidism.Despite early recognition and treatement, mortality is still 10 % and upto 30% when presents with Hyperthermia, Cardiac failure and arrhythmia.
Precipitating Factors of Thyrotoxic Crisis-

Acute illness (e.g. stroke, infection, trauma, Diabetic Ketoacidosis or DKA)
Surgery (especially subtotal thyroidectomy when patient is ill-prepared)
Radioiodine treatment of a patient with partially treated …

Hypothyroidism : Clinical featues, diagnosis and treatment

Hypothyroidism : Clinical featues, diagnosis and treatment

Hypothyroidism is an endocrine disorder caused by deficiency of Thyroid hormone which results in systemic manifestation of a spectrum of symptoms.
Prevalence : Primary hypothyroidism is 1:100 but increases upto  1:20 if patients with subclinical hypothyroidism are included. But  in Mountainous region of Nepal, Iodine deficiency is common.
Female:male= 6:1
Etiology or Causes of Hypothyroidism:
Autoimmune or Hashimoto’s Disease and Iatrogenic causes account for maore …

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