Opioid Poisoing- Clinical features, Diagnosis and emergency management
Opioids are among the commonly misused substance by drug abusers around the world. Opioids come in various forms – Heroin , Morphine, Methadone, Coedine, Pethidine, Dihydrocoedeine.
Opioids are a class of drugs derived from the extracts of plant- opium poppy. Used as Analgesics but most opiates give a feeling of euphoria and a …
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July 20, 2010 # 6:56 pm # Emergengy medicine, Pharmacology # No CommentORGANOPHOSPHORUS POISONING
December 12, 2009 # 9:28 am # Emergengy medicine # 3 CommentsORGANOPHOSPHORUS POISONING
-OP compounds are widely used as pesticides, for eradication of vectors.
Malathion,Fenthion,Methamidophos,Diazinon,Chlorpyrifos,Parathion are the common insecticides.
CLINICAL PRESENTATION
Acute cholinergic syndrome:- occur within minutes of exposure.
Pungent garlic like odour in breath, vomit and clothing; Muscarinic effects -miosis , bronchorrhoea, bronchospasm, salivation , lacrimation , abdominal pain , bradycardia
Nicotinic effects- Muscle fasciculation, hyper-reflexia, flaccid muscle weakness with reduced tendon reflexes
CNS effects- headache, …
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