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Cancer medicine in the era of Next Generation Sequencing: Solving the Puzzle

Cancer medicine in the era of Next Generation Sequencing: Solving the Puzzle

Cancer as a disease still remains one of the most complex human illness with high degree of morbidity and mortality across the globe. The involvement of multiple risk factors (genetics, hereditary, environmental etc) further adds a huge challenge in understanding the cancer puzzle even with numerous intensive research on this deadly disease. This year marks over six decades since James …

Migraine Headache

Migraine Headache

Migraine Headache: Introduction,Clinical Features, Trigger factors,Diagnosis,management and Prophylaxis
Introduction:
Migraine is the 2nd most common cause of headache affecting 15% of women and 6 % of men worldwide. It is an episodic headache associated with certain features like sensitivity to light light, sound or movement . Nausea vomiting often accompany the headache.
Triggers for Migraine Headache:
Hormonal Changes:- Changes during menses, pregnancy, menopause, and …

Sickle Cell Disease: A Primer

Sickle Cell Disease: A Primer

Background:
Sickle cell disease (SCD) or sickle cell anemia (SCA) is a hemoglobinopathy wherein abnormal hemoglobin is produced. It was first noted by James Herrick a medical student of African descent in 1911, when he discovered sickle-shaped erythrocytes while examining a student’s blood. Linus Pauling further categorized the disorder by noting that when the haemoglobin from an individual with sickle cell …

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