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Gullian Barre Syndrome – Post-infectious demyelinating polyneuropathy

Gullian Barre Syndrome – Post-infectious demyelinating polyneuropathy

Definition
Guillain-Barre syndrome is a postinfectious polyneuropathy involving mainly motor but sometimes also sensory and autonomic nerves. Guillain-Barré syndrome is an acute demyelinating disorder of the peripheral nervous system that results from an aberrant immune response directed at peripheral nervesThe pathogenesis of GBS is believed to be an abnormal immune response to an antecedent event, most commonly an infection. (Nelson Textbook of …

GFR Calculations- Accepted formula

GFR Calculations- Accepted formula

Estimated values
A number of formulae have been devised to estimate GFR or Ccr values on the basis of serum creatinine levels.

Estimated creatinine clearance rate (eCCr) using Cockcroft-Gault formula
A commonly used surrogate marker for estimate of creatinine clearance is the Cockcroft-Gault formula, which in turn estimates GFR: It is named after the scientists who first published the formula, and it …

Management of Patient with Acute Coronary Syndrome

Management of Patient with Acute Coronary Syndrome

A) Initial management:

Person with prolonged cardiac pain: Deep, visceral, heavy, squeezing, crushing, typically radiating to arms, lower jaw, abdomen, back but above umbilicus
Call 102, come to nearby hospital
Duty doctor: suspect ACS
Do 12 lead ECG (1st investigation to be done)

B) Further management is based on ECG results:
1. No ST Elevation (Unstable angina, NSTEMI):

ECG changes: ST deviation and T wave inversion (in …

Understanding Hypothyroidism

Understanding Hypothyroidism

Thyroid Hormones
The major thyroid hormones are T0-T2 and T3-T4.
T0 through T2 are considered inert hormones. They appear to be byproducts of thyroid hormone synthesis and do not appear to have any function in the body.
T3 and T4 are the hormones associated with hypothyroidism, and they play a crucial role in your metabolism. T3 is the primary hormone used to fuel …

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