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Newer Antibiotics and their Uses – Review

Newer Antibiotics and their Uses – Review

FDA Approved Antibiotics which are marketed internationally. The problem of the antibiotic resistance has been over-viewed in the previous article. Here are the latest antibiotics in current use.

Oxazolidinones
In clinical use: Linezolid   In clinical trials: Radezolid, torezolid.
Effective against Organisms-
–gram-positive bacteria including MRSA, VRE and Streptococcus pneumoniae.
–Mycobacterium tuberculosis and Nocardia.
Linezolid- 1st to be approved this millenium
Indicated-
–VRE infections
–nosocomial and community-acquired pneumonia,
–skin and soft tissue infections.(SSTIs)

Bacteriostatic against …

Antibiotic Resistance and Newer antibiotics- An overview

Antibiotic Resistance and Newer antibiotics- An overview

The need for novel antibacterials is a desparation today because of increasing resistance to the older ones.Three classes of drug-resistant bacteria are a major cause of concern-
–Methicillin -resistantStaphylococcus aureus (MRSA),
–multidrug-resistant (MDR) and pan-drug-resistant (PDR) gram-negative bacteria, which include strains of Acinetobacter baumannii, Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa,
–MDR and  extensively-drug-resistant (XDR) strains of Mycobacterium tuberculosis (MDR-TB and XDR-TB).
Drug Resistance
•Multidrug resistance (MDR) bacteria – non-susceptibility …

How to Study Pharmacology : Study plan MBBS

How to Study Pharmacology : Study plan MBBS

A complete new and difficult topic and relatively unheard of terminologies and words are met in the subject called Pharmacology. This is what makes it one of the most difficult subject to learn and often needs mugging up of names of drugs. But as you become familiar to the terminologies and start getting comfortable with the drugs, pharmacology becomes fun. …

Thalidomide induced Teratogenecity: Phocomelia

Thalidomide induced Teratogenecity: Phocomelia

Thalidomide taken during Pregnancy, in 1960s caused a horror outbreak  of a birth defects of limbs called Phocomelia
Labeled as pregnancy category X,  the teratogenicity of  thalidomide is  most severe. Lipid soluble and readily crosses the placenta, so it should never be taken by pregnant women or those who could become pregnant.
Thalidomide was released in 1956 as a mild sedative used …

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