Thalidomide taken during Pregnancy, in 1960s caused a horror outbreak  of a birth defects of limbs called Phocomelia
Labeled as pregnancy category X,  the teratogenicity of  thalidomide is  most severe. Lipid soluble and readily crosses the placenta, so it should never be taken by pregnant women or those who could become pregnant.
Thalidomide was released in 1956 as a mild sedative used …

Laxatives (purgatives, aperients) are foods, compounds, or medication that promote and facilitate bowel evacuation by acting locally to stimulate intestinal peristalsis, to soften bowel contents, or both. Laxatives are generally indicated in constipation (bowel movements that are infrequent and/or hard to pass). With constipation stools are usually hard, dry, small in size, and difficult to eliminate. At least 1 bowel …

War Fiction By Medchrome
In 2012, war broke out. Soon the war was fought all over the world. This time the enemy were not human neither aliens. They were invisible , tiny but lethal. The war was between doctors and bacteria.
Doctors used every weapon they had – antibiotics but the bacteria had become too resistant.
“Once upon a time, penicillin was discovered …

Unfractioned Heparin-
Unfractioned Heparin- is derived from  porcine intestinal mucosa or bovine lung tissue. UFH catalyzises that inactivation of thrombin and factor Xa by inhibiting Anti-thrombin III.  At usual dose it prolongs TT and aPTT and has a minimal effect on PT/INR.
Benefits of UFH-

1. The effect of UFH normalizes within hours of discontinuation
2. It is reversible with Protamine Sulphate.
3. Can be …

Enzymes are the extremely selective biocatalysts synthesized by living cells. Therapeutic enzymes are those enzymes which can be used medically either isolately or adjunctly with other therapies with the purpose of treatment of various diseases safely. Use of these enzymes as drugs for the treatment of medical problems forms the basis for “Therapeutic use of enzymes”. The cost of such …