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Pathogenesis of Toxic Shock Syndrome (TSS)

Pathogenesis of Toxic Shock Syndrome (TSS)

Toxic shock syndrome (TSS) is a toxin mediated, rare, life threatening, systemic illness caused due to infection of Staphylococcus aureus (staphylococcal toxic shock) and Streptococcus pyogens (rarer called streptococcal toxic shock). While the syndrome often occurs in menstruating women, it can also affect men, children and postmenopausal women.
Sources of infection:

Vagina (superabsorbent tampon use)
Barrier contraceptives (diaphragm or vaginal sponge)
Nose (nasal …

Complications of Blood transfusion and their management

Complications of Blood transfusion and their management

A. Transfusion Reactions:
May be allergic or hemolytic
1. Hemolytic reactions: can be acute or delayed
Acute Hemolytic reactions:

It is usely due to ABO incompatibility, there is intravascular hemolysis
As low as 10 ml of blood can produce hemolytic reactions
Clinically, patients presents with complains of pain and burning in vein and fever with chills and rigor, nausea and vomiting, flushing, chest …

Therapeutic Use of Enzymes

Therapeutic Use of Enzymes

Enzymes are the extremely selective biocatalysts synthesized by living cells. Therapeutic enzymes are those enzymes which can be used medically either isolately or adjunctly with other therapies with the purpose of treatment of various diseases safely. Use of these enzymes as drugs for the treatment of medical problems forms the basis for “Therapeutic use of enzymes”. The cost of such …

Microbiology of Dermatophytes

Microbiology of Dermatophytes

Dermatophytosis:
Tinea or ringworm (dermatophytoses) are defined as cutaneous fungal infections of keratinized tissues (hair, nail, skin,etc.) by a group of related mould fungi called dermatophytes. Skin acts as a barrier to fungal infection. The fatty acid content and acid pH of skin, ciliary mucosal epithelia of respiratory tract and humoral factors restrict the growth of dermatophytes to the outer layers …

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